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Cancer Treatment Cancer's mechanism and structure of cancer treatment

Takashima clinic’s “cancer treatment” is a treatment that is based on cancer’s mechanism in order to treat cancer.If the reasons of why cancer develops and its structures is known, each individual can get individual treatment.

In reality, cancer cells are born from a genetic abnormality and every day it is said there are over 5000 that are born. They do not develop into cancer depending on immune cells that attack and make them disappear. However when the balance of genes breaks down, the cells that have become dominated by the abnormal genes becomes cancer cells.

Cells that have become cancer cells do not have the function that normal cells have that “disappear by itself when it becomes stage = self death (apoptosis)” and continue to increase in numbers. This is cancer’s mechanism. As the balance between regular genes and abnormal genes collapses (※1) cells become cancer cells and grow rapidly and the number of immune cells that play a role in attacking cancer cells becomes insufficient (※2) and are no longer able to stop the growth of cancer cells; therefore cancer develops.


Are you now able to see the structure of cancer treatment based on the mechanism of cancer?
In this way, treatment based on evidence is the primary focus at Takashima Clinic.

The process of cancer treatment based on the mechanism

In cancer treatment, there is a correct process. And please keep the following as a premise.The patient before the anticancer drug has much higher therapeutic effect.Based on this premise, the ideal order for cancer treatment will be explained. The figure below is an example of a typical treatment.

Below it the ideal order.
Everyone’s situation is put against the cancer board and specialists from every field together will develop a treatment policy suitable for each individual.

1. Increase the effects of treatment with gene treatment
This means becoming dominant with normal genes. It increases the sensitivity to attack against cancer and increases the therapeutic effect. So first in order to put the body in a state that increases therapeutic effect, the body needs to go through gene therapy.

2. Collect healthy immune cells = selective immune cell culture therapy (blood collection)

In order to attack cancer cell, healthy immune cells are necessary. There is no point in increasing weakened immune cells. Therefore, it is very important to collect blood for culture before the body weakens. At Takashima clinic, “selective culture” means to select and cultivate only the most necessary and effective cells and cultivate them. Immunotherapy specialist, Director Takashima and specialists for each field on the Cancer Board decide for each individual which immune cells to cultivate.

3. Mark cancer cells with dendritic cell vaccine therapy
When an immune cell attacks a cancer cell, it is necessary to mark this. The dendritic cell works to attach this marker. It is very important to put more marks before an immune cell makes its attack.

4. Return cultivated strong immune cells back into the body = selective immune cell culture therapy
By cultivating healthy immune cells and returning them into the body, the ability to attack the cancer cells increases. Immune cells do not only attach cancer cells. Immune cells also have the power to protect the body against other diseases.

5. Increase all treatment effects using high concentration vitamin C drip therapy
This extremely versatile treatment not only increases the power of immune cells to fight cancer cells and normal genes but it has also been confirmed that the very high concentration of vitamin C (megavitamin) has the same effect as anticancer drugs.

Cancer Treatment

Gene Therapy

Gene therapy is a treament method where a damaged gene is relaced by a healthy gene of the same kind which will activate over the damaged gene,so that the mutated gene will be inactivated. By inactivating the mutated gene, cancer cells can be inactivated. When a healthy gene is activated over a damaged gene, sensitivity of cells increase,th us effects of anti-cancer drugs, attacks by immune cells, and high-dose Vitamin C incr eases. Further, the "TRAIL gene", one of the genes replaced in gene therapy, is a gene used w hen the immune cell called NK cell attacks cancer cells, so it will increase the effec t of immune cell curlturing therapy.

Anti-cancer Drug Sensitivity Examination

This is an examination to test sensitivity to anti-cancer drugs. This enables to deter mine which anti-cancer drugs are effective before treatment, so the risk of "anti-canc er drug treatment with no effect" decreases.

Selective Immune Cell Culturing Treatment at Takashima Clinic

Cells which attack and destroy cancel cells are called "immune cells". The are several kinds of immune cells, and each have different ways of attacking the c ells. Selective immune cell culturing treatment is a treatment where the cells are se lected, cultured and increased according to the individual's condition, and returned i nto the patient's body to increase the power to attack. The immune cells used for this culturing is extracted from blood. The more healthy the patient is when the immune cells are extracted, the stronger the immune cells that are increased. The "TRAIL gene", one of the genes replaced in gene therapy, is a gene used when the i mmune cell called NK cell attacks cancer cells. (Link to website of Louis Pasteur Center for Medical Research, where Dr. Takashima is the Head of Immunotherapeutic Research)

Dendritic Cell Vaccine Therapy

Immune cell called T-cells are one of the cells that attack cancer cells. However, th e T-cells need instructions which says "attack the cells with a marker"in order to att ack the cancer cells. Dendritic cells put markers on cancer cells. And, it instructs the T-cells to attack the marked cells. The T-cells then start to a ttack only the marked cells (=cancer cells). The T-cells which received instructions from the dendritic cells and begins to attack are called killer T-cells. Dendritic cell vaccine therapy is a therapy which replaces dendriticl cells into the b ody in order to continuously increase killer T-cells.

High-Dose Vitamin C

A very large quantity of Vitamin C is called a prodrug and functions like medicine ins ide a human body. Vitamin C, when oxidized, has a strong antioxidant effect and generates a massive amou nt of hydrogen peroxide. When injected to the blood, hydrogen peroxide is neutralized by healthy cells, but can cer cells die, not being able to neutralize hydrogen peroxide. The effects achieved by increasing the dose of Vitamin C in blood are being able to attach cancer cells with anti-cancer power equal to that of anti-cancer drugs can safely continue until the cancer cells are gone, as it does not develop resistance With the above, by adding this as adjunct therapy to each of the combined therapy, we can hope to avoid cessation of treatment caused by side effects in anti-cancer drug tr eatment, and improve treatment effect with increased power of immune cells in immunoth erapy. (Link to website of Japan Collge of Intravenous Therapy, where Dr. Takashima is a boar d member.)

Selective Anti-Cancer DrugTreatment

Anti-cancer drug treatment attacks healthy cells also. This is why immunity decreases greatly during anti-cancer drug treatment. When the proliferation capability of cancer cells exceeds the ability of anti-cancer d rugs to attack, we change the anti-cancer drug to a stronger kind, or extend the perio d of administration. As administration of anti-cancer drugs continue, cancer cells develop the ability to f ight anti-cancer drugs. This is called resistance. Cancer cells with resistance fend off attacks from anti-cancer drugs and continue to p roliferate. For this reason, we at Takashima Clinic consider that during anti-cancer drug treatmen t it is very important that immunity does not decrease small dose of anti-cancer drugs are used to fight cancer = use effective anti-cancer d rugs.

More than 90% prevention rate of relapse achieved

If nothing is done, the possibility of cancer recurring is high.

At Takashima clinic, we proactive try to prevent the recurrence of cancer.
To prevent cancer cells from growing again, it is necessary to bring down cancer cells every day with gene therapy and immune cells.
This is called preventive treatment for recurrence.

At Takashima clinic, we recommend preventative treatments such as treatment that continues immune cell culture therapy and high-concentration vitamin C drip infusion therapy. These types of treatments that prevent recurrence has a record of preventing recurrence of over 90%.

Blood cancer examination
is absolutely necessary to as part of recurrence prevention treatment.
This is an examination to determine whether or not there is cancer somewhere by measuring the number of circulating cancer cells (CTC) and circulating stem cells (CSC) in the blood.

Because we can find cancer that may not appear in an image examination and detect recurrence earlier, we increase the possibility of remission. It is usually too late when finding cancer through PET examination or tumor marker.

Special examination indispensable for cancer treatment

Cancer examination is not only an image examination.
There are two tests recommended by Takashima Clinic that are effective cancer tests.

“Blood cancer cell test”
“Anticancer drug susceptibility test”


These two are state of the art tests that can detect cancer earlier than image examinations.

Blood cancer cell examination is an examination to find the number of cancer cells in the blood and an examination to “detect cancer before found in an image” and “check if cancer has not recurred”.

The cancer that appears in the image examination is “cancer that has developed 10 years ago”. Before it has reached this point, you can treat cancer more quickly, more easily, and reliably.

The anticancer drug susceptibility test is an “examination to judge whether an anticancer drug is effective.”
Until now, depending on the type of cancer, the anticancer drug was selected. Therefore, it was not known whether an anticancer drug would work unless it was administered.

The anticancer drug susceptibility test is an examination that determines “the most effective anticancer drug for you” and is done before anticancer drug treatment. You no longer have to do unnecessary anticancer drug treatments like before.

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